Install your D16 plugin from the Splice desktop client and restart your machine.
To get your D16 plugin up and running in Ableton you need to check Ableton's AU/VST settings.
Navigate to :
File and Folder
Make sure "Use AudioUnits/VST" are all checked and hit Rescan.
Windows users will only have the option "VST Plugin Custom Folder", manually navigate to the location you installed your D16 Plugin. By default the Windows installation path is: C:\Program Files\VSTPlugins\D16 Group\ . Please note the D16 plugins only support 64 bit DAWs, there is no 32 bit version.